Centre for Targeted Protein Degradation
The Centre for Targeted Protein Degradation (CeTPD) is bolstering the University of Dundee’s world-leading position in a field that is revolutionising drug discovery.
Targeted protein degradation
![CeTPD](/sites/default/files/styles/content_summary/public/2021-10/cetpd-logo.png?h=ae1281eb&itok=PK9o9yiQ)
Targeted protein degradation co-opts the cell’s natural disposal systems to remove disease-causing proteins and is applicable to diverse therapeutic areas including oncology, dermatology, immunology, neuroscience and respiratory diseases.
This entirely new approach is revolutionising drug discovery by making the treatment of diseases previously thought to be undruggable a reality.
CeTPD is part of the University’s School of Life Sciences, one of the UK’s top institutions for research into biological sciences.
Dundee researchers and teams led by Professor Alessio Ciulli have previously revealed fundamental insights into the working of the degrader molecules that they have designed and that are used across the globe. Collaborations with pharma companies Boehringer Ingelheim and Almirall amongst others are helping to advance the field, while the biopharmaceutical company Amphista Therapeutics is a University of Dundee spin-out of the Ciulli Lab.
Our new translational research centre will build on this established excellence to innovate groundbreaking science and accelerate translation by developing and inspiring the next generation of scientists and leaders.
![Professor Alessio Ciulli in a lab with researchers](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/media_container_width_free_image/public/2021-09/PROTAC-5I0A2640.jpg?itok=T0gpJtCp)
Professor Alessio Ciulli
Stories
![Delegates sitting in a lecture theare for the TPD in Focus symposium](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card/public/2024-05/CeTPD%20in%20Focus.jpg?itok=2QO1DcLo)
Press release
One of Scotland’s most significant scientific success stories in recent times has been celebrated at a special event hosted by the University of Dundee.
Press release
Two University of Dundee initiatives are to benefit from millions of pounds of UK Government investment.
![Members of the CeTPD team accept their award at the ceremony](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card/public/2024-03/cetpd%20award.jpg?itok=avMS7SZF)
Press release
Ground-breaking drug discovery work at the University of Dundee has been honoured at a national awards ceremony.
![Professor Alessio Ciulli in from of a University of Dundee crest](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card/public/2024-02/Alessio%20Ciulli%20-%20CeTPD.jpg?itok=Dff2pGr0)
Press release
World-leading expertise from the University of Dundee’s Centre for Targeted Protein Degradation (CeTPD) will contribute to a new, global effort to tackle some of the most significant challenges posed by cancer.
![Professor Alessio Ciulli in from of a University of Dundee crest](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card/public/2024-02/Alessio%20Ciulli%20-%20CeTPD.jpg?itok=Dff2pGr0)
Press release
A breakthrough class of molecular glue identified at the University of Dundee could pave the way for a new generation of drugs to target cancers and neurodegenerative diseases.
News
Review of the Year 2023 took place this week with the Dean, Julian Blow sharing the highlights of activity within the School from 2023.
![Group photo of attendees at the first Scottish cryoEM symposium](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card/public/2023-12/first-scottish-cryoEM-group-image.jpg?itok=x0ccY0n2&h=20641c8e)
News
A one day symposium for the Scottish cryo-EM community took place on 30 November 2023
![Members of CeTPD and RIS stand with their award](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card/public/2023-11/team-award.jpg?itok=nF6gVQQV&h=5b8657fc)
Press release
The commercial achievements of a University of Dundee spinout have been recognised with a top prize at a major awards ceremony.