Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU)
We study how eukaryotic cell biology is shaped by protein phosphorylation and ubiquitylation. Driven by our curiosity and passion to understand living creatures, our work aims to change lives by helping to cure human disease.
The MRC Protein Phosphorylation and Ubiquitylation Unit (PPU) is a major research centre that focuses on the understanding of the biological roles of phosphorylation and ubiquitylation and how disruption of these processes cause human diseases such as neurodegeneration, cancer, hypertension and immune disorders.
The ultimate goal of the Unit’s research programmes is to help develop new improved strategies to treat disease. The MRC-PPU operates as a focal point between life scientists, pharmaceutical companies and clinicians to ensure that we make a critical contribution to medical research, together reaching a deeper understanding of disease.
Director
![Portrait photograph of Dario Alessi](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2020-05/dario-alessi-square.jpg?itok=tTeb44Z3&h=78a719da)
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General Manager
![Portrait photo of Paul Davies](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2021-10/paul-davies.jpg?itok=3kGbQuDK&h=664d2fc5)
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Academic staff
![Portrait photo of Philip Cohen](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2021-10/Philip-Cohen.jpg?itok=FSOwouhW&h=75503d7e)
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![Virginia De Cesare](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2023-11/Virginia-De-Cesare.jpg?itok=2s0L4uFZ&h=0c0736ab)
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![Portrait photo of Greg Findlay](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2021-10/Greg-Findlay.jpg?itok=1xc4V1Y7&h=a51cdb52)
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![Portrait photo of Ian Ganley](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2021-10/ian-ganley.jpg?itok=pjtxLU00&h=05948e7e)
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![Yogesh Kulathu](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2023-03/yogesh_kulathu.jpg?itok=t4RFd7ef&h=536536d6)
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![Karim Labib](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2023-07/Karim_Labib_SLS.jpg?itok=CJbyXu-M&h=237196af)
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![Amos Liang](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2023-07/Amos-Liang.jpg?itok=h8ZxQjIp&h=e45ddaa2)
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![Ralitsa Madsen](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2023-08/Ralitsa-Madsen.jpg?itok=e6OV3M3G&h=0abe802b)
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![Chiara Maniaci](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2023-02/ChiaraManiaci.jpg?itok=bLSy9twr&h=7f028c66)
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![Portrait photo of Miratul Muqit](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2019-09/miratul-muqit.jpg?itok=Vyt8gqHI&h=3d933492)
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![Portrait photo of John Rouse](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2021-10/John-Rouse.jpg?itok=OXoAvhPF&h=96118562)
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![Portrait photo of Adrien Rousseau](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2021-09/Adrien-Rousseau.jpg?itok=A4DmRUEx&h=64da8378)
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![Gopal Sapkota](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2023-08/Gopal-Sapkota.jpg?itok=MwiYpKMZ&h=957fa4c2)
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![Portrait photo of Mahima Swamy](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2021-10/mahima-swamy.jpg?itok=hzvHcnCf&h=89af840a)
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![Kirby Swatek](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2023-06/Kirby-Swatek.jpg?itok=bz2-j5Zw&h=55cb1816)
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![Portrait photo of Satpal Virdee](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card_portrait/public/2021-10/satpal-virdee.jpg?itok=6jHg1J5F&h=5a4a328e)
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Key contacts
Name | Role | |
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Alison Hart | Senior Administrator | A.Y.Hart@dundee.ac.uk |
Edwin Allen | Lab Manager | e.allen@dundee.ac.uk |
Renata Soares | Mass Spectrometry Facilities Manager | r.filipesoares@dundee.ac.uk |
Publications
Stories
![Outrun Therapeutics logo](/sites/default/files/styles/card/public/2024-05/OutrunTx_Logo_RGB%5B57%5D_0.png?h=c71d0c67&itok=xHlE26jW)
News
A University of Dundee spinout company has been named among the world’s most promising start-ups after being nominated for a prestigious global prize.
![Professor Miratul Muqit](/sites/default/files/styles/card/public/2023-05/Professor%20Miratul%20Muqit%20-%20UoD.png?h=4dd76f1a&itok=EHPXrLof)
Press release
Scientists at the University of Dundee have uncovered the inner relay of a molecular switch that protects the brain against the development of Parkinson’s disease.
![From left Nicole Ong, Vasudha Tandon, Vikram Tejwani, Rotimi Fasimoye, Catriona Liggett](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card/public/2024-04/sls-symposium-poster-prize-winners_0.jpg?itok=UhSiS4IG&h=63d103ee)
News
Last month, the School of Life Sciences held their annual Research Symposium at Crieff Hydro. Talks were given by Principal Investigators, Facility Leads, Postdoctoral Researchers and PhD students including SLS Prize winners.
![Professor Satpal Virdee](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card/public/2024-04/Satpal%20Virdee%202024%20-%20reduced.jpg?itok=E9lmW7iT)
News
A University of Dundee spinout has announced a multi-million pound deal to develop first-in-class therapeutics that restore the body's natural disease suppression processes.
![Didier Ndeh (left) and Ralitsa Madsen (right)](/sites/default/files/styles/card/public/2024-04/didier-ralitsa.png?h=0834e036&itok=mDeYOYAf)
News
Didier Ndeh and Ralitsa Madsen have been promoted to Principal Investigator positions within the School of Life Science, following recent Roundtable Interviews.
![Gabrielle Asamoah and Nneka Igwebuike](http://cdn-acquia.dundee.ac.uk/sites/default/files/styles/card/public/2024-04/Gabrielle%20Asamoah%20and%20Nneka%20Igwebuike.jpg?itok=CJi5crbf)
News
The School of Life Sciences (SLS) have recently welcomed the first two recipients of scholarships for Black British students on our Masters by Research (MbR) course.